Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 410
interventional 309
Observational 91
Registry 10

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 206
Drug|placebo 62
Biological 12
Other 8
Biological|Drug 6
Biological|placebo 4
Biological|Drug|placebo 2
Device|Drug 2
Drug|Other 2
Procedure 2
Behavioral 1
Drug|Genetic 1
Genetic 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
China 67
Korea, Republic of 38
United States 23
NA 18
Hong Kong 9
Taiwan 9
Italy 5
Japan 5
New Zealand 5
Singapore 5
Netherlands 4
Canada 3
India 3
United States|New Zealand 3
Australia|Hong Kong|Korea, Republic of|New Zealand|Thailand 2
Australia|New Zealand 2
Bangladesh 2
Bulgaria 2
Canada|France|Germany 2
China|Hong Kong 2
China|Korea, Republic of 2
France 2
Germany 2
Hong Kong|Korea, Republic of 2
Russian Federation 2
Spain 2
United States|Australia|Canada|Korea, Republic of|New Zealand 2
United States|Canada|Hong Kong|Italy|Korea, Republic of|New Zealand|Taiwan|United Kingdom 2
United States|Canada|Hong Kong|New Zealand|United Kingdom 2
United States|New Zealand|Singapore|Taiwan 2
Argentina|Brazil|Germany|Thailand 1
Australia 1
Australia|Bulgaria|China|Hong Kong|Korea, Republic of|New Zealand|Singapore|Taiwan|Thailand 1
Australia|Hong Kong|Korea, Republic of|New Zealand|Singapore|Taiwan|Thailand 1
Australia|Hong Kong|Korea, Republic of|Taiwan|United Kingdom 1
Australia|Netherlands|Poland|Thailand 1
Austria|Bulgaria|Germany|Greece|Italy|Russian Federation|Spain|Turkey 1
Belgium 1
Belgium|Bulgaria|France|Georgia|Germany|Malaysia|Moldova, Republic of|Romania|Spain|Taiwan 1
Belgium|France|Germany|Italy|Poland|Spain|United Kingdom 1
Belgium|Germany|Philippines|United Kingdom 1
Belgium|Germany|United Kingdom 1
Bulgaria|China|Hong Kong|Korea, Republic of|New Zealand|Poland|Taiwan|United Kingdom 1
Bulgaria|Former Yugoslavia 1
Bulgaria|Hong Kong|Italy|Netherlands|New Zealand|Taiwan|Thailand|United Kingdom 1
Cambodia 1
Canada|China|France|Hong Kong|Korea, Republic of|New Zealand|Spain|Taiwan|Thailand|United Kingdom 1
Canada|Korea, Republic of|Taiwan 1
Canada|Moldova, Republic of|Ukraine 1
Canada|Netherlands 1
Canada|United Kingdom 1
China|France|Korea, Republic of|Singapore|Taiwan|Thailand|United States|Australia|Canada 1
China|Hong Kong|Japan|Korea, Republic of|Philippines|Singapore 1
China|Netherlands 1
China|Netherlands|Poland|Romania|Turkey 1
China|United States|Canada|France 1
China|United States|Korea, Republic of|Singapore|Taiwan 1
Czechia|United States|Belgium|Brazil|Canada|China|France|Germany|Hong Kong|Italy|Japan|Korea, Republic of|Malaysia|Poland|Russian Federation|Spain|Thailand|Turkey|United Kingdom 1
Denmark|Ethiopia|Norway|Sweden 1
Estonia|Latvia|Lithuania 1
France|Germany|Italy|Netherlands|Poland|Romania|Spain 1
France|United States|Australia|Bulgaria|Canada|Czech Republic|Germany|Greece|Italy|Netherlands|New Zealand|Poland|Spain|Turkey|United Kingdom 1
Germany|Hong Kong|Korea, Republic of|New Zealand|Singapore|United Kingdom 1
Germany|United States|Australia|Canada|France|Hong Kong|New Zealand|Poland|Singapore|Taiwan|United Kingdom 1
Hong Kong|Korea, Republic of|Malaysia|New Zealand|Singapore|Taiwan 1
Hong Kong|Korea, Republic of|Singapore|Taiwan|Vietnam 1
Hong Kong|New Zealand|Singapore 1
Hong Kong|Singapore|Taiwan|Thailand 1
Iran, Islamic Republic of 1
Italy|United States|Australia|Belgium|Bulgaria|China|Germany|Israel|Poland|Russian Federation|Ukraine|United Kingdom 1
Korea, Republic of|Moldova, Republic of|New Zealand|Thailand|Ukraine 1
Korea, Republic of|Taiwan 1
Moldova, Republic of 1
Morocco 1
Poland 1
Thailand 1
Thailand|Australia|Brazil|China|Hong Kong|Korea, Republic of|New Zealand|Russian Federation|Singapore|Taiwan 1
Turkey 1
United States|Argentina|Australia|Brazil|Canada|France|India|Italy|Mexico|Poland|Russian Federation|South Africa|Turkey 1
United States|Argentina|Australia|Brazil|France|Italy|Korea, Republic of|Spain|Taiwan 1
United States|Argentina|Belgium|Brazil|Canada|Korea, Republic of|Taiwan|United Kingdom 1
United States|Argentina|Belgium|Canada|Germany|Greece|India|Israel|Korea, Republic of|Poland|Romania|Russian Federation|Taiwan|United Kingdom 1
United States|Australia|Belgium|Germany|Italy|Malaysia|Romania|Russian Federation|Taiwan|Turkey|Ukraine|United Kingdom 1
United States|Australia|Brazil|Canada|China|France|Germany|Israel|Korea, Republic of|New Zealand|Poland|Puerto Rico|Singapore|Switzerland|Taiwan|Thailand|United Kingdom 1
United States|Australia|Brazil|Canada|Greece|Hong Kong|India|Indonesia|Italy|Korea, Republic of|Malaysia|Philippines|Poland|Russian Federation|Singapore|Taiwan|Thailand|Turkey 1
United States|Australia|Brazil|China|France|Germany|Hong Kong|Korea, Republic of|New Zealand|Russian Federation|Singapore|Taiwan|Thailand 1
United States|Australia|Bulgaria|Canada|Czech Republic|France|Germany|Greece|Italy|Netherlands|New Zealand|Poland|Spain|Turkey|United Kingdom 1
United States|Australia|Canada|China|Czech Republic|France|Germany|Hong Kong|India|Israel|Italy|Korea, Republic of|New Zealand|Poland|Puerto Rico|Singapore|Spain|Taiwan|Thailand|Turkey|United Kingdom 1
United States|Australia|Canada|China|France|Germany|India|Israel|Korea, Republic of|Latvia|Malaysia|New Zealand|Poland|Russian Federation|Singapore|Spain|Taiwan|Thailand|Turkey|United Kingdom|Vietnam 1
United States|Australia|Canada|China|France|Israel|New Zealand|Singapore|Taiwan|Thailand|United Kingdom 1
United States|Australia|Canada|France|Germany|Greece|Hong Kong|India|Italy|Korea, Republic of|Netherlands|Poland|Portugal|Romania|Singapore|Spain|Taiwan|Turkey|United Kingdom 1
United States|Australia|Canada|New Zealand|United Kingdom 1
United States|Australia|China|Hong Kong|Korea, Republic of|New Zealand|United Kingdom 1
United States|Australia|Hong Kong|New Zealand|Philippines|Singapore|Taiwan|Thailand 1
United States|Belgium|Canada|China|France|Germany|Hong Kong|Italy|Japan|Korea, Republic of|Malaysia|Poland|Russian Federation|Spain|Taiwan|Thailand|Turkey|Ukraine|United Kingdom 1
United States|Belgium|Canada|Hong Kong|India|Korea, Republic of|New Zealand|Romania|Russian Federation|Taiwan 1
United States|Brazil|Mexico|Puerto Rico|South Africa 1
United States|Bulgaria|France|Poland|Romania|Spain|Turkey 1
United States|Canada 1
United States|Canada|France|Germany|Greece|Italy|Poland|Singapore|Spain|Taiwan|Turkey 1
United States|Canada|Hong Kong|Indonesia|Philippines|Singapore|Taiwan|Thailand 1
United States|Canada|Hong Kong|Italy|Korea, Republic of|Spain|Taiwan|United Kingdom 1
United States|Canada|Italy|Korea, Republic of|Netherlands|New Zealand 1
United States|Canada|Italy|Korea, Republic of|New Zealand|Romania 1
United States|Canada|New Zealand 1
United States|France|Germany|Spain 1
United States|India 1
United States|India|Korea, Republic of|Romania|Taiwan 1
United States|Japan|Korea, Republic of|Taiwan 1
United States|Korea, Republic of|Spain|Thailand|Turkey|United Kingdom 1

Sites per Study

Site_count Study_Count
1 133
2 17
3 9
4 12
5 2
6 6
7 8
8 6
9 10
10 5
11 5
12 12
13 3
14 6
15 5
16 1
17 3
18 3
19 4
20 3
21 7
22 2
23 3
24 5
25 3
27 3
28 3
30 1
31 2
32 2
33 1
34 1
35 1
37 1
38 1
39 5
42 1
43 1
44 1
45 1
48 1
54 1
55 1
67 1
68 1
74 1
76 1
80 1
87 1
112 1
171 1

Phase

Phase Study_Count
Phase 4 100
Phase 2 70
Phase 3 53
Phase 1 49
N/A 23
Phase 1/Phase 2 11
Phase 2/Phase 3 3

Number of Arms

Number_of_Arms Count_of_Studies
1 58
2 127
3 42
4 22
5 7
6 10
7 2
8 4
9 2
10 1
12 1
18 1
NA 32

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 6.000 9.00000 8.00000 5.000 90.0 6.0000 11.0000
1st Qu. 60.000 29.00000 30.00000 42.000 105.0 62.0000 73.5000
Median 124.000 48.00000 48.00000 80.000 120.0 131.0000 131.0000
Mean 145.087 55.91837 53.63636 121.942 157.0 248.5745 563.4747
3rd Qu. 183.500 80.00000 67.50000 150.000 190.5 277.0000 254.5000
Max. 380.000 175.00000 121.00000 1053.000 261.0 1869.0000 30000.0000

Trial Group Type

group_type Group_Count
Experimental 479
Active Comparator 129
Placebo Comparator 70
NA 32
Other 24
No Intervention 23

Intervention Model

intervention_model Study_Count
Parallel Assignment 205
Single Group Assignment 74
Sequential Assignment 11
NA 9
Crossover Assignment 8
Factorial Assignment 2

Primary Purpose

primary_purpose Study_Count
Treatment 280
Prevention 12
Other 8
NA 5
Basic Science 2
Health Services Research 1
Screening 1

Observational Studies

Studies by Country

Country Study_Count
China 29
Korea, Republic of 9
Taiwan 8
United States 6
Germany 5
NA 5
Netherlands 3
France 2
Hong Kong 2
Senegal 2
United States|Canada 2
Zambia 2
Australia 1
Australia|France|Hong Kong|Italy|Korea, Republic of|New Zealand|Russian Federation|Singapore|Taiwan|Thailand 1
Austria|Bahrain|Bangladesh|Bosnia and Herzegovina|Bulgaria|China|Egypt|France|Germany|Hong Kong|India|Indonesia|Ireland|Jordan|Korea, Republic of|Lebanon|Macedonia, The Former Yugoslav Republic of|Morocco|New Zealand|Pakistan|Poland|Portugal|Romania|Saudi Arabia|Thailand|United Arab Emirates|United Kingdom 1
Austria|Bulgaria|China|France|Germany|Greece|Italy|Korea, Republic of|New Zealand|Poland|Portugal|Romania|Taiwan|Thailand|United Kingdom 1
Brazil 1
Bulgaria 1
China|United States|Argentina|Brazil|Canada|Colombia|Czechia|France|Germany|Greece|India|Italy|Korea, Republic of|Mexico|Philippines|Poland|Portugal|Romania|Russian Federation|Singapore|Spain|Taiwan|Thailand|Turkey 1
Egypt 1
Gambia|Senegal 1
Greece 1
India 1
India|United States|Argentina|Brazil|China|France|Greece|Italy|Peru|Philippines|Poland|Romania|Russian Federation|Singapore|Spain|Taiwan|Thailand|United Kingdom 1
Moldova, Republic of 1
Serbia 1
Spain 1
United States|Australia|Bulgaria|Canada|Germany|Hungary|Italy|New Zealand|Romania|Turkey 1

Sites per Study

Site_count Study_Count
1 58
2 4
4 4
5 2
6 3
7 2
8 2
9 1
11 1
12 1
16 1
19 1
22 1
26 1
27 1
28 1
50 1
84 1
86 1
88 1
90 1
249 1
290 1

Enrollment Metrics

Measure Observational
Min 1.000
1st Qu 105.000
Median 400.000
Mean 1061.802
3rd Qu 883.000
Max 20000.000

Observation Model

observational_model Study_Count
Cohort 70
NA 6
Other 5
Case-Only 4
Case-Control 3
Case Control 2
Defined Population, Natural History 1

Time Perspective

time_perspective Study_Count
Prospective 57
Retrospective 23
Other 5
Cross-Sectional 4
Longitudinal, Prospective 1
NA 1

Registries

Studies by Country

Country Study_Count
China 3
Korea, Republic of 3
Cameroon 1
NA 1
Spain 1
Taiwan 1

Sites per Study

Site_count Study_Count
1 9
45 1

Enrollment Metrics

Measure Registries
Min 55.00
1st Qu 245.75
Median 488.00
Mean 20505.20
3rd Qu 738.50
Max 200000.00

Registry Model

observational_model Study_Count
Cohort 8
Case-Control 1
NA 1

Time Perspective

time_perspective Study_Count
Prospective 8
Cross-Sectional 1
Other 1

Follow-up

target_duration Study_Count
10 Years 3
5 Years 2
1 Day 1
1 Year 1
2 Weeks 1
20 Years 1
48 Weeks 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03361956 An Efficacy, Safety, and Pharmacokinetics Study of JNJ-56136379 in Participants With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT03361956 Active, not recruiting Janssen Sciences Ireland UC 2019-09-05
NCT04082338 Chronic HBV Management for Asian American https://ClinicalTrials.gov/show/NCT04082338 Active, not recruiting Temple University 2021-09-30
NCT03320616 EYP001a Food Effect Study in Subjects With Chronic Hepatitis B Virus (HBV) Infection https://ClinicalTrials.gov/show/NCT03320616 Completed Enyo Pharma 2017-10-12
NCT03272009 Evaluation of the Safety and Pharmacology of EYP001 in HBV Subjects https://ClinicalTrials.gov/show/NCT03272009 Completed Enyo Pharma 2018-07-30
NCT03258710 A Study of Switching From Entecavir to Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03258710 Completed GlaxoSmithKline 2018-12-28
NCT03241641 Switching From TDF to TAF vs. Maintaining TDF in Chronic Hepatitis B With Resistance to Adefovir or Entecavir. https://ClinicalTrials.gov/show/NCT03241641 Active, not recruiting Asan Medical Center 2020-03-31
NCT03180619 Safety and Efficacy of Switching to Tenofovir Alafenamide (TAF) From Tenofovir Disoproxil Fumarate (TDF) and/or Other Oral Antiviral Treatment (OAV) https://ClinicalTrials.gov/show/NCT03180619 Active, not recruiting Gilead Sciences 2019-03-27
NCT03180333 The Tolerability and Pharmacokinetics Clinical Trial of Metacavir Enteric-coated Capsules in Healthy Adult Volunteers https://ClinicalTrials.gov/show/NCT03180333 Completed Guangzhou Yipinhong Pharmaceutical CO.,LTD 2012-08-31
NCT03173599 The Safety and Tolerability of Metacavir Enteric-coated Capsules in Healthy Adult Volunteers https://ClinicalTrials.gov/show/NCT03173599 Completed Guangzhou Yipinhong Pharmaceutical CO.,LTD 2011-04-30
NCT03123653 To Study the Efficacy of PEG-IFN Alpha in HBeAg Negative Chronic Hepatitis B Patients After Stopping Nucleotide Analogue Therapy. https://ClinicalTrials.gov/show/NCT03123653 Active, not recruiting Institute of Liver and Biliary Sciences, India 2019-09-17
NCT03084250 The Investigation of Peginterferon Alfa-2a on Optimal in Chronic Hepatitis B Patients Who Have a High Risk of HCC https://ClinicalTrials.gov/show/NCT03084250 Active, not recruiting Shanghai Nanhui Nanhua Hospital 2023-04-01
NCT03038113 A Study to Evaluate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of RO7062931in Healthy Volunteers and Subjects With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03038113 Completed Hoffmann-La Roche 2019-10-18
NCT03023787 Study of Hepalatide(L47) at Phase Ib in Healthy Volunteers https://ClinicalTrials.gov/show/NCT03023787 Completed Shanghai HEP Pharmaceatical Co., Ltd. 2016-12-31
NCT03020745 A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3389404 in Chronic Hepatitis B (CHB) Subjects https://ClinicalTrials.gov/show/NCT03020745 Completed GlaxoSmithKline 2019-01-28
NCT03013556 Study on an Optimal Antiviral Treatment in HBeAg Positive Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT03013556 Recruiting Ruijin Hospital 2020-06-30
NCT02992704 Peg-interferon for Inactive Chronic Hepatitis B Carriers https://ClinicalTrials.gov/show/NCT02992704 Active, not recruiting National University Health System, Singapore 2019-08-31
NCT02991638 Efficacy and Safety of Ibrutinib in Patients With CLL and Other Indolent B-cell Lymphomas Who Are Chronic Hepatitis B Virus Carriers or Occult Hepatitis B Virus Carriers https://ClinicalTrials.gov/show/NCT02991638 Recruiting The University of Hong Kong 2020-12-31
NCT02981602 Safety, Tolerability, Pharmacokinetics and Antiviral Activity of IONIS-HBVRx in Treatment-Naïve Patients With Chronic HBV Infection https://ClinicalTrials.gov/show/NCT02981602 Completed Ionis Pharmaceuticals, Inc. 2019-12-18
NCT02979613 Efficacy and Safety of Switching From TDF to TAF in Adults With Chronic Hepatitis B Who Are Virologically Suppressed https://ClinicalTrials.gov/show/NCT02979613 Completed Gilead Sciences 2018-09-10
NCT02964910 A Phase â…£ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients ) https://ClinicalTrials.gov/show/NCT02964910 Completed Xiamen Innovax Biotech Co., Ltd 2017-08-31
NCT02956850 A Study in Healthy Volunteers and in Participants With Chronic Hepatitis B to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7020531 https://ClinicalTrials.gov/show/NCT02956850 Recruiting Hoffmann-La Roche 2021-02-10
NCT02952924 A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected Participants https://ClinicalTrials.gov/show/NCT02952924 Recruiting Hoffmann-La Roche 2021-06-30
NCT02937779 Tenofovir As Prevention Of Hepatitis b Mother-to-child Transmission https://ClinicalTrials.gov/show/NCT02937779 Active, not recruiting French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) 2020-03-31
NCT02908191 A Study in Healthy Volunteers and Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02908191 Completed Assembly Biosciences 2018-03-31
NCT02881008 Myrcludex B vs Entecavir in Patients With HBeAg Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02881008 Completed Hepatera Ltd. 2014-10-04
NCT02838810 The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg https://ClinicalTrials.gov/show/NCT02838810 Recruiting Third Affiliated Hospital, Sun Yat-Sen University 2019-12-31
NCT02792088 Study to Assess the Antiviral Activity and Safety Endpoints for the Treatment of Besifovir 150mg Compared to Tenofovir 300mg in Chronic Hepatitis B Patients Who Have Resistance to Nucleoside Analogues https://ClinicalTrials.gov/show/NCT02792088 Recruiting IlDong Pharmaceutical Co Ltd 2019-03-31
NCT02791269 A Study of Peginterferon Alfa-2a in Participants With Chronic Hepatitis B Virus (HBV) in an Expanded Access Program https://ClinicalTrials.gov/show/NCT02791269 Completed Hoffmann-La Roche 2008-07-31
NCT02774837 Tenofovir Versus Tenofovir + Telbivudine for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02774837 Active, not recruiting National University Health System, Singapore 2020-07-31
NCT02745704 The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg https://ClinicalTrials.gov/show/NCT02745704 Recruiting Third Affiliated Hospital, Sun Yat-Sen University 2019-04-30
NCT02743182 HBsAg Loss Adding Pegylated Interferon in HBeAg-negative Patients https://ClinicalTrials.gov/show/NCT02743182 Completed Parc de Salut Mar 2018-10-31
NCT02738554 Off Treatment Durability in Chronic Hepatitis B With Good Immune Control https://ClinicalTrials.gov/show/NCT02738554 Completed The University of Hong Kong 2020-01-31
NCT02662712 A Study of Orally Administered JNJ-56136379 to Evaluate Safety, Tolerability and Pharmacokinetics After Single Ascending Doses and One Multiple Dose Regimen in Healthy Participants (Part I), and After Multiple Dose Regimens in Participants With Chronic Hepatitis B (Part II) https://ClinicalTrials.gov/show/NCT02662712 Completed Janssen Sciences Ireland UC 2018-06-29
NCT02646189 Therapeutic Safety and Efficacy of REP 2139 (REP 9AC’) in HBV Infected Patients https://ClinicalTrials.gov/show/NCT02646189 Completed Replicor Inc. 2013-08-31
NCT02646163 Therapeutic Safety and Efficacy of REP 9AC (REP 2055) in HBV or HCV Infected Patients https://ClinicalTrials.gov/show/NCT02646163 Completed Replicor Inc. 2012-12-31
NCT02631096 Study of ARB-001467 in Subjects With Chronic HBV Infection Receiving Nucleos(t)Ide Analogue Therapy https://ClinicalTrials.gov/show/NCT02631096 Completed Arbutus Biopharma Corporation 2018-05-18
NCT02612506 Safety and Pharmacokinetic Study of Hepalatide(L47) in Healthy Volunteers https://ClinicalTrials.gov/show/NCT02612506 Completed Shanghai HEP Pharmaceatical Co., Ltd. 2016-08-31
NCT02604823 A Study of Peginterferon Alfa-2a (Pegasys) in Participants With Hepatitis B E-Antigen (HBeAg)-Positive Chronic Hepatitis B Virus (HBV) https://ClinicalTrials.gov/show/NCT02604823 Completed Hoffmann-La Roche 2005-11-30
NCT02600117 Use of TDF in Patients With Inactive Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT02600117 Enrolling by invitation University Health Network, Toronto 2022-05-31
NCT02598063 A Study to Evaluate Efficacy and Safety of Peginterferon Alfa-2a (Pegasys) and Adeforvir Dipivoxil (ADV) in Participants With Lamivudine-Resistant Hepatitis B e Antigen (HBeAg)-Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02598063 Completed Hoffmann-La Roche 2009-04-30
NCT02589457 Study to Compare the Safety and Pharmacokinetics of CKD-390 Tablet With Viread® Tablet https://ClinicalTrials.gov/show/NCT02589457 Completed Chong Kun Dang Pharmaceutical 2015-12-31
NCT02570191 A Study of PEGASYS (Peginterferon Alfa-2a [40KD]) in Patients With Hepatitis B e Antigen (HBeAg)-Negative Chronic Hepatitis B Virus (HBV) https://ClinicalTrials.gov/show/NCT02570191 Completed Hoffmann-La Roche 2007-02-28
NCT02569372 A Phase 1 Study of GC1102 (Recombinant Hepatitis B Immunoglobulin) in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT02569372 Completed Green Cross Corporation 2017-10-12
NCT02932150 Tenofovir Alafenamide (TAF) in Children and Adolescents With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT02932150 Recruiting Gilead Sciences 2023-02-28
NCT02505009 Efficacy of HBV Vaccine in Consolidation of Nucleos(t)Ide Analogues Therapy https://ClinicalTrials.gov/show/NCT02505009 Completed Chang Gung Memorial Hospital 2018-12-21
NCT02431312 Phase I Study of INO-1800 With or Without INO-9112 + EP in Chronic Hepatitis B Subjects https://ClinicalTrials.gov/show/NCT02431312 Completed Inovio Pharmaceuticals 2018-05-22
NCT02428400 Safety and Tolerability of TG1050: A Dose-finding Study https://ClinicalTrials.gov/show/NCT02428400 Completed Transgene 2018-11-30
NCT02401737 Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patients https://ClinicalTrials.gov/show/NCT02401737 Completed Novira Therapeutics, Inc. 2016-05-18
NCT02391805 A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infection https://ClinicalTrials.gov/show/NCT02391805 Completed Hoffmann-La Roche 2017-10-16
NCT02366208 Phase II Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02366208 Completed Jiangsu Hansoh Pharmaceutical Co., Ltd. 2013-06-30
NCT02364336 Add-on Peginterferon Following Nucleos(t)Ide Analogue Treatment https://ClinicalTrials.gov/show/NCT02364336 Completed National Institutes of Health Clinical Center (CC) 2018-05-21
NCT02360592 Combination Therapy With Interferon Plus Interleukin 2 and Hepatitis B Vaccine in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT02360592 Completed Tongji Hospital 2016-12-31
NCT02355951 Non-investigational Study to Evaluate Adenovirus Serotype 5 (Ad5) Neutralizing Antibodies (nAb) in Patients With Chronic Hepatitis B Virus (HBV) Mono-infection https://ClinicalTrials.gov/show/NCT02355951 Completed Transgene 2016-02-29
NCT02338674 TDF and LdT in Immune-tolerant CHB Patients Awaiting Assisted Reproduction https://ClinicalTrials.gov/show/NCT02338674 Completed Fuzhou General Hospital 2016-10-31
NCT02332473 A Prospective Study of Combination of Peginterferon Alfa-2b (40kD, Y-shape) and GM-CSF in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02332473 Completed Xiamen Amoytop Biotech Co., Ltd. 2016-02-29
NCT02300688 Bioequivalence Study to Compare the Pharmacokinetics of Besifovir in Healthy Adult Volunteers https://ClinicalTrials.gov/show/NCT02300688 Completed IlDong Pharmaceutical Co Ltd 2015-02-28
NCT02287857 Efficacy and Safety of Domestic Tenofovir Tablets in Chinese Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02287857 Recruiting Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 2019-10-31
NCT02263079 A Study of Pegylated Interferon Alfa-2A in Combination With Lamivudine or Entecavir Compared With Untreated Control Group in Children With Hepatitis B Envelope Antigen (HBeAg)-Positive Chronic Hepatitis B (CHB) in the Immune-Tolerant Phase https://ClinicalTrials.gov/show/NCT02263079 Completed Hoffmann-La Roche 2020-01-29
NCT02249988 Clinical Efficacy of ABX203 Therapeutic Vaccine in HBeAg Negative Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02249988 Completed Abivax S.A. 2016-12-31
NCT02224456 Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosis https://ClinicalTrials.gov/show/NCT02224456 Active, not recruiting GlaxoSmithKline 2020-12-02
NCT02202473 Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects https://ClinicalTrials.gov/show/NCT02202473 Completed Southeast University, China 2014-02-28
NCT02195518 Tenofovir Disoproxil Fumarate (TDF) 300mg 3 Years RD Therapy Chinese Chronic Hepatitis B (CHN) CHB Multiple Nucleos(t)Ide Analogues (NAs) Failure Points Pts PH4 PMS Study https://ClinicalTrials.gov/show/NCT02195518 Completed GlaxoSmithKline 2018-08-14
NCT02174276 Safety and Efficacy of GS-4774 in Combination With Tenofovir Disoproxil Fumarate (TDF) for the Treatment of Participants With Chronic Hepatitis B (CHB) and Who Are Currently Not on Treatment https://ClinicalTrials.gov/show/NCT02174276 Completed Gilead Sciences 2016-02-17
NCT02166047 Safety and Efficacy of GS-9620 for the Treatment of Chronic Hepatitis B Virus in Virally-Suppressed Subjects https://ClinicalTrials.gov/show/NCT02166047 Completed Gilead Sciences 2016-05-31
NCT02112799 Safety and Efficacy Study of NVR 3-778 in Healthy Volunteers and Hepatitis B Patients https://ClinicalTrials.gov/show/NCT02112799 Completed Novira Therapeutics, Inc. 2016-05-18
NCT02097004 Study of Therapeutic Vaccination With Intensified Schedule Plus Pegasys Dual Therapy on Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT02097004 Completed Seoul National University Hospital 2018-01-31
NCT02081469 Prophylaxis of CHB Patients With Malignant Tumor Receiving Chemotherapy https://ClinicalTrials.gov/show/NCT02081469 Completed Chang Gung Memorial Hospital 2019-08-05
NCT02068365 An Open-label Trial of 48-week Peginterferon Alfa-2a (PEGASYS) to Assess the Sustained Response of Chronic Hepatitis B Patients With HBeAg Seroconversion on Nucleot(s)Ide Analogue Therapy https://ClinicalTrials.gov/show/NCT02068365 Completed Chinese University of Hong Kong 2019-06-30
NCT01277601 Efficacy & Safety of Tenofovir Disoproxil Fumarate (TDF) Plus Peginterferon α-2a (Peg-IFN) Versus TDF or Peg-IFN Monotherapy in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01277601 Completed Gilead Sciences 2014-08-31
NCT03753074 Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines https://ClinicalTrials.gov/show/NCT03753074 Recruiting Asan Medical Center 2023-12-31
NCT01651403 Efficacy, Safety and Tolerability of Tenofovir Disoproxil Fumarate Versus Placebo in Pediatric Participants With Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT01651403 Active, not recruiting Gilead Sciences 2017-08-07
NCT03357822 A Real-World Study of Pegylated Interferon In Nucleoside-treated Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03357822 Recruiting Tongji Hospital 2022-01-25
NCT03356834 Change of Renal Function and Bone Mineral Density in CHB Patients Switch From TDF to TAF vs. Maintaining TDF https://ClinicalTrials.gov/show/NCT03356834 Recruiting Humanity and Health Research Centre 2022-10-31
NCT01997944 Recombinant Human Serum Albumin/Interferon alpha2a Fusion Protein Phase Ib Study in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT01997944 Completed Beijing Bio-Fortune Ltd. 2014-09-30
NCT01943799 Safety and Efficacy of GS-4774 for the Treatment of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01943799 Completed Gilead Sciences 2014-09-09
NCT01937806 Phase 3 and Extensional Study of Besifovir https://ClinicalTrials.gov/show/NCT01937806 Active, not recruiting IlDong Pharmaceutical Co Ltd 2016-02-29
NCT01926288 Efficacy and Safety of Entecavir Maleate Tablets in Chinese Patients With Hepatitis B https://ClinicalTrials.gov/show/NCT01926288 Completed Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 2014-03-31
NCT01913431 Baracle Tab. ® Versus Baraclude Tab.® for Patients With HBeAg Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01913431 Completed Dong-A ST Co., Ltd. 2015-11-06
NCT01892241 Efficacy and Safety of Peginterferon a-2a in Patients of Chronic Hepatitis B With Spontaneous Decline of HBV DNA https://ClinicalTrials.gov/show/NCT01892241 Completed Third Affiliated Hospital, Sun Yat-Sen University 2012-11-30
NCT01887275 A Control Study to Evaluate The Efficacy And Safety of Ozone-therapy in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01887275 Completed Nanfang Hospital of Southern Medical University 2013-02-28
NCT01817725 Hepatitis B Vaccine in Chronic Hepatitis B Patients With Low Serum HBsAg https://ClinicalTrials.gov/show/NCT01817725 Completed Chang Gung Memorial Hospital 2016-02-29
NCT01813487 Study of the Immunogenicity and Efficacy of HBsAg Vaccine in Combination With Standard Antiviral Therapy With HB110E https://ClinicalTrials.gov/show/NCT01813487 Completed Genexine, Inc. 2013-07-31
NCT01787279 An Expanded Access Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01787279 Completed Hoffmann-La Roche 2009-05-31
NCT01760122 Efficacy and Safety of Peginterferon Alfa-2b in HBeAg Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01760122 Completed Xiamen Amoytop Biotech Co., Ltd. 2015-07-31
NCT01745822 Maternal Antiviral Prophylaxis to Prevent Perinatal Transmission of Hepatitis B Virus in Thailand https://ClinicalTrials.gov/show/NCT01745822 Completed Institut de Recherche pour le Developpement 2016-12-31
NCT01743079 Study of Telbivudine and Lamivudine to Prevent Vertical Transmission of Hepatitis B https://ClinicalTrials.gov/show/NCT01743079 Completed Beijing YouAn Hospital 2013-07-31
NCT01732367 TDF VS LAM + ADV in LAM + ADV Treated LAM-resistant CHB Patients With Undetectable Hepatitis B Virus DNA https://ClinicalTrials.gov/show/NCT01732367 Completed Keimyung University Dongsan Medical Center 2016-03-31
NCT01728935 Tenofovir in Asian Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT01728935 Completed The University of Hong Kong 2012-11-30
NCT01711567 Tenofovir Disoproxil Fumarate vs. Entecavir in Chronic Hepatitis B Patients With Partial Virologic Response to Entecavir https://ClinicalTrials.gov/show/NCT01711567 Completed Korea University 2015-12-31
NCT01708889 Pharmacokinetic Study of BMS-914143 in Participants With Normal Renal Function and Mild, Moderate, Severe and End-stage Renal Dysfunction https://ClinicalTrials.gov/show/NCT01708889 Completed Bristol-Myers Squibb 2013-02-28
NCT01706575 A Study of Pegasys (Peginterferon Alfa-2a) Added to Nucleos(t)Ide Analogue Treatment in Participants With HBeAg-Negative Chronic Hepatitis B Genotype D Showing Stable Hepatitis B Virus (HBV) Deoxyribonucleic Acid (DNA) Suppression https://ClinicalTrials.gov/show/NCT01706575 Completed Hoffmann-La Roche 2013-09-30
NCT04365933 A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir https://ClinicalTrials.gov/show/NCT04365933 Recruiting Enyo Pharma 2021-01-31
NCT01697501 A Study Evaluating IL28B Polymorphism in Patients With HBeAg-Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML18253 https://ClinicalTrials.gov/show/NCT01697501 Completed Hoffmann-La Roche 2013-06-21
NCT01671787 A Phase 1b Study Assessing GS-7340 in Treatment-Naive Adults With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01671787 Completed Gilead Sciences 2013-04-30
NCT01641536 Tolerability, Immunogenicity and Efficacy of HB-110 Administered by Electroporation in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT01641536 Completed Genexine, Inc. 2012-12-31
NCT01639092 Tenofovir vs. Tenofovir Plus Entecavir in Entecavir-Resistant Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01639092 Completed Asan Medical Center 2018-03-29
NCT01639066 Tenofovir Plus Entecavir vs. Tenofovir in Adefovir-Resistant Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01639066 Completed Asan Medical Center 2017-09-22
NCT01595685 Telbivudine Versus Entecavir in Reducing Serum HBsAg Levels in Patients With HBeAg-positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01595685 Completed Asan Medical Center 2014-12-31
NCT01590654 A Study Evaluating GS-9620 in Virologically Suppressed Subjects With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT01590654 Completed Gilead Sciences 2013-11-30
NCT01590641 A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01590641 Completed Gilead Sciences 2013-09-30
NCT01546116 Adefovir and Lamivudine for Entecavir Resistance (ALTER Study) https://ClinicalTrials.gov/show/NCT01546116 Completed Korea University 2012-02-29
NCT01532843 Lowering Viral Load With Nucleos(T)Ide Analogues Prior to Peginterferon Treatment to Ncrease Sustained Response in CHB https://ClinicalTrials.gov/show/NCT01532843 Completed Foundation for Liver Research 2015-08-31
NCT01524679 Peg-interferon ADDed to an Ongoing Nucleos(t)Ide Based Treatment in Patients With Chronic Hepatitis B to Induce Decrease of HBs-Antigen https://ClinicalTrials.gov/show/NCT01524679 Completed Johannes Gutenberg University Mainz 2017-08-28
NCT01522625 Tenofovir in Chronic Hepatitis B With Mild ALT Elevation https://ClinicalTrials.gov/show/NCT01522625 Completed E-DA Hospital 2018-11-30
NCT01521975 A Two-year Study of Telbivudine in HBeAg Negative Hepatitis https://ClinicalTrials.gov/show/NCT01521975 Completed Third Affiliated Hospital, Sun Yat-Sen University 2014-02-28
NCT01519960 A Study of Pegasys (Peginterferon Alfa-2a) Versus Untreated Control in Children With HBeAg Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01519960 Active, not recruiting Hoffmann-La Roche 2015-07-09
NCT01519921 A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Positive Chronic Hepatitis B. https://ClinicalTrials.gov/show/NCT01519921 Completed Hoffmann-La Roche 2008-06-30
NCT01480622 Pharmacokinetic (PK) Profiles of Tenofovir Disoproxil Fumarate (TDF) 300 mg in Healthy Chinese Subjects https://ClinicalTrials.gov/show/NCT01480622 Completed GlaxoSmithKline 2011-12-30
NCT01480492 Effect of Antiviral Therapy on Host Immune in Patients With Chronic Hepatitis B Virus(HBV) Infection https://ClinicalTrials.gov/show/NCT01480492 Completed Changhai Hospital 2011-10-31
NCT01480284 Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B Untreated With Nucleic Acid Analogue https://ClinicalTrials.gov/show/NCT01480284 Completed GlaxoSmithKline 2013-01-31
NCT01475851 Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B With Poor Response to Other Drugs https://ClinicalTrials.gov/show/NCT01475851 Completed GlaxoSmithKline 2013-06-30
NCT01471535 HBsAg Clearance in Inactive Chronic HBsAg Carriers After Interferon Treated https://ClinicalTrials.gov/show/NCT01471535 Completed Beijing Ditan Hospital 2012-12-31
NCT01438424 Safety and Antiviral Activity of Entecavir in Participants With Chronic Hepatitis B Following Monotherapy in Other Entecavir Trials https://ClinicalTrials.gov/show/NCT01438424 Completed Bristol-Myers Squibb 2009-12-31
NCT01412567 Vaccine+HBIG Versus Vaccine+Placebo for Newborns of HBsAg+ Mothers https://ClinicalTrials.gov/show/NCT01412567 Completed Govind Ballabh Pant Hospital 2010-06-30
NCT01373684 PEG-interferon Alfa-2a add-on Study in HBeAg Negative Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT01373684 Completed Foundation for Liver Research 2019-10-28
NCT01369212 Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir Versus Tenofovir Monotherapy in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01369212 Active, not recruiting National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2020-07-31
NCT01353742 Lamivudine and Adefovir Dipivoxil Fixed Dose Combination https://ClinicalTrials.gov/show/NCT01353742 Completed GlaxoSmithKline 2011-04-12
NCT01337791 Efficacy, Safety and Tolerability of Telbivudine in HBeAg Positive Chronic Hepatitis B Pregnant Women With Elevated Alanine Aminotransferase Levels https://ClinicalTrials.gov/show/NCT01337791 Completed Southeast University, China 2009-12-31
NCT01326546 Therapeutic Hepatitis B Vaccine (Mimogen-based) Joint Entecavir in Treating Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT01326546 Completed Chongqing Jiachen Biotechnology Ltd. 2014-01-31
NCT01320943 Stopping TDF Treatment After Long Term Virologic Suppression in HBeAg-negative CHB https://ClinicalTrials.gov/show/NCT01320943 Completed Gilead Sciences 2016-07-28
NCT04225715 A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT04225715 Recruiting Hoffmann-La Roche 2021-12-18
NCT04423393 Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT04423393 Recruiting Vir Biotechnology, Inc. 2022-08-31
NCT04398134 A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT04398134 Recruiting Assembly Biosciences 2023-01-19
NCT04289987 A Study to Evaluate the Efficacy and Safety of Therapeutic Hepatitis B Vaccine https://ClinicalTrials.gov/show/NCT04289987 Recruiting CHA Vaccine Institute Co., Ltd. 2021-08-19
NCT04271592 A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adults https://ClinicalTrials.gov/show/NCT04271592 Recruiting Assembly Biosciences 2020-11-03
NCT04248426 A Phase 1 Double-Blinded Study for Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ATI-2173 in Healthy Subjects and Subjects With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT04248426 Recruiting Antios Therapeutics, Inc 2021-08-31
NCT04201808 Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides https://ClinicalTrials.gov/show/NCT04201808 Recruiting New Discovery LLC 2021-09-30
NCT04195074 Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b https://ClinicalTrials.gov/show/NCT04195074 Recruiting Third Affiliated Hospital, Sun Yat-Sen University 2023-12-31
NCT04189276 Safety and Efficacy of Therapeutic Hepatitis B Adenovirus Injection (T101) Combined With Nucleoside (Acid) Analogues in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT04189276 Recruiting Tasly Tianjin Biopharmaceutical Co., Ltd. 2020-12-31
NCT04182321 Adding Metformin to the Standard Treatment for Patients With HBeAg-Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT04182321 Recruiting Beijing 302 Hospital 2021-12-31
NCT04180150 A Study of TQ-A3334 Combined With Entecavir in the Treatment of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT04180150 Recruiting Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 2020-09-30
NCT04157699 An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Tenofovir in Naive Patients With Chronic Hepatitis b https://ClinicalTrials.gov/show/NCT04157699 Recruiting Qilu Pharmaceutical Co., Ltd. 2020-12-31
NCT04157257 An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Entecavir or Tenofovir in Patients With Chronic Hepatitis b Who Have Received Nucleoside (Acid) Therapy https://ClinicalTrials.gov/show/NCT04157257 Recruiting Qilu Pharmaceutical Co., Ltd. 2020-12-31
NCT04142762 A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults https://ClinicalTrials.gov/show/NCT04142762 Completed Assembly Biosciences 2020-01-12
NCT04133259 Evaluate the Efficacy and Safety of HLX10 in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT04133259 Recruiting Henlix, Inc 2022-04-30
NCT04129554 A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT04129554 Recruiting Janssen Sciences Ireland UC 2022-01-31
NCT04112147 A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT04112147 Recruiting Chung Shan Medical University 2020-06-30
NCT04102176 Halting Nucleoside Analogues in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT04102176 Recruiting National University Health System, Singapore 2021-03-31
NCT04083716 A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy Adults https://ClinicalTrials.gov/show/NCT04083716 Completed Assembly Biosciences 2019-10-05
NCT04070079 Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B: https://ClinicalTrials.gov/show/NCT04070079 Recruiting University Health Network, Toronto 2022-08-30
NCT04069858 Maintaining Antiviral Efficacy After Switching to Generic Entecavir 1 mg for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT04069858 Active, not recruiting Korea University 2019-03-01
NCT04035837 The Clinical Cure Project of Chronic Hepatitis B in China https://ClinicalTrials.gov/show/NCT04035837 Recruiting Third Affiliated Hospital, Sun Yat-Sen University 2021-12-30
NCT04023721 Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor https://ClinicalTrials.gov/show/NCT04023721 Active, not recruiting Spring Bank Pharmaceuticals, Inc. 2020-06-30
NCT03982186 A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT03982186 Recruiting Janssen Sciences Ireland UC 2021-03-31
NCT03933384 Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03933384 Recruiting Taichung Veterans General Hospital 2022-12-31
NCT03905655 Study of Nitazoxanide Compared to Placebo in Subjects With HBeAG-Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03905655 Recruiting Romark Laboratories L.C. 2022-12-01
NCT03847246 Bioequivalence Study of Entecavir Tablets and Baraclude® Under Fasting Condition in Chinese Healthy Volunteers https://ClinicalTrials.gov/show/NCT03847246 Completed Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 2018-12-28
NCT03801798 A Study of GC1102(Recombinant Hepatitis B Immunoglobulin) in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT03801798 Active, not recruiting Green Cross Corporation 2021-12-31
NCT03801538 The Optimizing Treatment of Peginterferon Alpha in Chronic Hepatitis B Patients With Low Level HBsAg https://ClinicalTrials.gov/show/NCT03801538 Active, not recruiting Third Affiliated Hospital, Sun Yat-Sen University 2020-12-31
NCT03792919 Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK) https://ClinicalTrials.gov/show/NCT03792919 Recruiting Humanity & Health Medical Group Limited 2023-12-31
NCT03780543 A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT03780543 Active, not recruiting Assembly Biosciences 2021-06-30
NCT03778567 Renoprotective Effects of Telbivudine in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03778567 Completed The University of Hong Kong 2016-06-16
NCT03772249 Study of Safety and Tolerability of DCR HBVS https://ClinicalTrials.gov/show/NCT03772249 Recruiting Dicerna Pharmaceuticals, Inc. 2020-05-31
NCT03762681 A Study of RO7239958 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers and Participants With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT03762681 Active, not recruiting Hoffmann-La Roche 2021-03-13
NCT03759782 Ribavirin to Enhance Hepatitis B Virus Nucleotide Analog Antiviral Activity https://ClinicalTrials.gov/show/NCT03759782 Recruiting Ottawa Hospital Research Institute 2020-01-03
NCT03714152 A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03714152 Recruiting Assembly Biosciences 2020-08-31
NCT03681132 The Norwegian Nucleoside Analogue Stop Study https://ClinicalTrials.gov/show/NCT03681132 Active, not recruiting Oslo University Hospital 2022-10-01
NCT03672188 Study of VIR-2218 in Healthy Volunteers and Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03672188 Active, not recruiting Vir Biotechnology, Inc. 2021-03-31
NCT03662568 A Drug-drug Interaction (DDI) Study of Morphothiadine Mesilate/Ritonavir in Healthy Subjects https://ClinicalTrials.gov/show/NCT03662568 Completed Sunshine Lake Pharma Co., Ltd. 2018-07-31
NCT03638076 The Safety, Antiviral Activity, and Pharmacokinetics of Morphothiadine Mesilate Capsules https://ClinicalTrials.gov/show/NCT03638076 Recruiting Sunshine Lake Pharma Co., Ltd. 2018-12-09
NCT03615066 Safety, Tolerability, and Antiviral Activity of Selgantolimod in Viremic Adults With Chronic Hepatitis B Who Are Not Currently on Treatment https://ClinicalTrials.gov/show/NCT03615066 Active, not recruiting Gilead Sciences 2019-12-12
NCT03585322 APG-1387 Study of Safety, Tolerability ,PK/PD in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03585322 Recruiting Ascentage Pharma Group Inc. 2021-10-30
NCT03577171 A Study Evaluating ABI-H0731+ NUC vs NUC Alone for the Treatment of Viremic HBeAg-positive, CHB Patients https://ClinicalTrials.gov/show/NCT03577171 Completed Assembly Biosciences 2019-06-21
NCT03576066 A Study Evaluating ABI-H0731 as Adjunctive Therapy in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03576066 Completed Assembly Biosciences 2019-07-05
NCT03575208 Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03575208 Recruiting National Institutes of Health Clinical Center (CC) 2022-05-30
NCT03546530 The Curative Effect and Security of Interferon Combined Resveratrol on HBeAg Positive Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT03546530 Completed First Hospital of Jilin University 2017-01-31
NCT03491553 Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Adults With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03491553 Active, not recruiting Gilead Sciences 2019-03-22
NCT03485534 Evaluate the Efficacy and Safety to Tenofovir Disoproxil in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT03485534 Recruiting Daewoong Pharmaceutical Co. LTD. 2020-10-30
NCT03471624 Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF) https://ClinicalTrials.gov/show/NCT03471624 Active, not recruiting Stanford University 2021-08-31
NCT03469583 Drug Drug Interaction Study for EYP001 With Entecavir https://ClinicalTrials.gov/show/NCT03469583 Completed Enyo Pharma 2018-06-20
NCT03463369 A First-In-Human Study to Evaluate Safety, Tolerability, Reactogenicity, and Immunogenicity of JNJ-64300535, a DNA Vaccine, Administered by Electroporation-Mediated Intramuscular Injection, in Participants With Chronic Hepatitis B Who Are on Stable Nucleos(t)Ide Therapy and Virologically Suppressed https://ClinicalTrials.gov/show/NCT03463369 Active, not recruiting Janssen Sciences Ireland UC 2021-03-23
NCT03439488 A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03439488 Completed Alios Biopharma Inc. 2019-10-10
NCT03434353 Study to Evaluate the Antiviral Activity of Inarigivir Soproxil (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB) https://ClinicalTrials.gov/show/NCT03434353 Active, not recruiting Gilead Sciences 2020-01-20
NCT03429439 Study on Effect of Intestinal Microbiota Transplantation in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03429439 Recruiting Zhongshan Hospital Xiamen University 2020-10-31
NCT01264367 A Study to Evaluate the Efficacy and Safety of Clevudine and Peg-interferon in Sequence Compared With Clevudine Alone in the Patients With HBeAg(+) Chronic Hepatitis B or Clevudine and Peg-interferon Sequential Treatment in Patients With Chronic Hepatitis B Who Have HBeAg(+) https://ClinicalTrials.gov/show/NCT01264367 Completed Bukwang Pharmaceutical 2013-08-31
NCT01264354 An Open Study to Evaluate the Efficacy, Safety of Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01264354 Completed Bukwang Pharmaceutical 2012-08-31
NCT01254994 The Efficacy and Safety of Entecavir Treatment of Patients With Acute on Chronic Hepatitis B Liver Failure https://ClinicalTrials.gov/show/NCT01254994 Completed Sun Yat-sen University 2009-07-31
NCT01237496 Analysis of HBV-Specific Immune Response in Patients With HBeAg Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a (40KD)) - Immunology Sub-Study of ML18253 https://ClinicalTrials.gov/show/NCT01237496 Completed Hoffmann-La Roche 2009-09-30
NCT01205165 An Open Label, Multi Centre Phase IV Study of Adefovir Dipivoxil in Korean Patients With Chronic Hepatitis B (CHB) https://ClinicalTrials.gov/show/NCT01205165 Completed GlaxoSmithKline 2006-04-28
NCT01192854 An Study of Efficacy and Safety of Clevudine https://ClinicalTrials.gov/show/NCT01192854 Completed Eisai Inc. 2011-05-31
NCT01143662 Efficacy and Safety of Ypeginterferon Alfa-2b in HBeAg Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01143662 Completed Xiamen Amoytop Biotech Co., Ltd. 2011-04-30
NCT01098006 A Study in Adult Subjects With Chronic Hepatitis B Infection to Support the Development of Immunological Assays https://ClinicalTrials.gov/show/NCT01098006 Completed GlaxoSmithKline 2012-02-20
NCT01095835 A Study of Pegylated Interferon Alfa-2a and Lamivudine in Patients With HBeAg-Negative Chronic Hepatitis B Virus (HBV) https://ClinicalTrials.gov/show/NCT01095835 Completed Hoffmann-La Roche 2010-01-31
NCT01088009 Efficacy Optimizing Research of Lamivudine Therapy https://ClinicalTrials.gov/show/NCT01088009 Completed Nanfang Hospital of Southern Medical University 2013-02-28
NCT01086085 A Study of Peginterferon Alfa-2a [PEGASYS] in Patients With Chronic Hepatitis B Who Are HBeAg Positive https://ClinicalTrials.gov/show/NCT01086085 Completed Hoffmann-La Roche 2013-03-31
NCT01079806 A Phase III Study of the Safety and Efficacy of Entecavir in Pediatric Patients With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT01079806 Completed Bristol-Myers Squibb 2013-03-31
NCT01063036 Efficacy and Safety Study of Entecavir Plus Tenofovir in Patients With Chronic Hepatitis B Who Failed Previous Treatment https://ClinicalTrials.gov/show/NCT01063036 Completed Bristol-Myers Squibb 2012-11-30
NCT01037166 Study in Japan of the Safety And Antiviral Activity in Adults With Chronic Hepatitis B Current Lamivudine Therapy https://ClinicalTrials.gov/show/NCT01037166 Completed Bristol-Myers Squibb 2005-02-28
NCT01037062 An Open-Label Rollover Study of Entecavir (BMS-200475) in Adults With Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT01037062 Completed Bristol-Myers Squibb 2006-12-31
NCT01026610 Safety and Efficacy Study of LB80380 in the Treatment-naive Patients of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01026610 Completed LG Life Sciences 2010-11-30
NCT01023230 A Study to Assess DV-601 in Subjects With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01023230 Completed Dynavax Technologies Corporation 2011-05-31
NCT01023217 Entecavir Plus Adefovir in Lamivudine-Resistant Chronic Hepatitis B Patients Who Fail Lamivudine Plus Adefovir https://ClinicalTrials.gov/show/NCT01023217 Completed Asan Medical Center 2012-07-31
NCT01022801 A Phase II Dose Response Study in Japan in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01022801 Completed Bristol-Myers Squibb 2005-03-31
NCT01020565 A Study in Japan of the Safety and Antiviral Activity With Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT01020565 Completed Bristol-Myers Squibb 2005-02-28
NCT01013272 Lamivudine Therapy in Patients With Prior Entecavir Treatment and Undetectable Viral Load https://ClinicalTrials.gov/show/NCT01013272 Completed The University of Hong Kong 2010-07-31
NCT00994773 Simvastatin for the Treatment of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00994773 Completed Bader, Ted, M.D. 2011-10-31
NCT00988767 Safety and Immunogenicity of a Naked DNA-based Vaccine Therapy in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00988767 Completed Institut National de la Santé Et de la Recherche Médicale, France 2003-11-30
NCT00975091 Continue Entecavir Rollover From China https://ClinicalTrials.gov/show/NCT00975091 Completed Bristol-Myers Squibb 2007-08-31
NCT00973219 Hepatitis B Surface Antigen(HBsAg) Loss in Chronic Hepatitis B Patients With Low Viral Load https://ClinicalTrials.gov/show/NCT00973219 Active, not recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2019-11-30
NCT00962975 A Study of Pegasys Monotherapy in Patients With Chronic Hepatitis B Who Have Participated in Previous Studies https://ClinicalTrials.gov/show/NCT00962975 Completed Hoffmann-La Roche 2013-05-31
NCT00962871 A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or Both https://ClinicalTrials.gov/show/NCT00962871 Completed Hoffmann-La Roche 2012-02-29
NCT00962533 EFFicacy Optimization Research of Telbivudine Therapy https://ClinicalTrials.gov/show/NCT00962533 Completed Nanfang Hospital of Southern Medical University 2012-04-30
NCT00940485 A Study of Combination or Sequential Treatment With PEGASYS (Peginterferon Alfa-2a) and Entecavir in Patients With HBeAg Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00940485 Completed Hoffmann-La Roche 2011-12-31
NCT00936715 Rollover Protocol Continued Access to Emtricitabine/Tenofovir Disoproxil Fumarate for Adults in United States https://ClinicalTrials.gov/show/NCT00936715 Completed Gilead Sciences 2015-11-30
NCT00927082 A Follow-Up Study to WV19432, to Evaluate Long Term Post-Treatment Effects of PEGASYS (Peginterferon Alfa-2a(40KD))in Patients With HBeAg Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00927082 Completed Hoffmann-La Roche 2014-11-30
NCT00922207 A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Adefovir or Entecavir in Patients With HBeAg-Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00922207 Completed Hoffmann-La Roche 2014-09-29
NCT00907894 Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00907894 Completed Novartis 2012-03-31
NCT00895713 Efficacy and Safety of Intramuscular HBIG Grifols for the Prevention of Recurrence After Liver Transplantation https://ClinicalTrials.gov/show/NCT00895713 Completed Grifols Biologicals, LLC 2005-06-30
NCT00895596 Safety and Efficacy Study of LB80380 in the Patients With Lamivudine-Refractory Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00895596 Completed LG Life Sciences 2006-08-31
NCT00883844 PEG-IFN in HBV Patients With Incomplete Response to NA https://ClinicalTrials.gov/show/NCT00883844 Completed Foundation for Liver Research 2012-06-30
NCT00877760 Augmenting Response to Entecavir With Peginterferon a-2a for the Treatment of HBeAg-positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00877760 Completed Foundation for Liver Research 2013-07-31
NCT00877149 Efficacy of Telbivudine Treatment at Long Term on the Absence of Liver Inflammation in Patients With Compensated Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00877149 Completed Novartis 2011-04-30
NCT00869778 Phase 2 Trial of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00869778 Completed Chongqing Jiachen Biotechnology Ltd. 2011-11-30
NCT00857675 A Efficacy and Safety Study of Adefovir Dipivoxil to Treat Chinese Patients With HBeAg+ve Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00857675 Completed GlaxoSmithKline 2008-03-31
NCT04168333 Safety and Efficacy of Therapeutic Hepatitis B Adenovirus Injection (T101) in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT04168333 Completed Tasly Tianjin Biopharmaceutical Co., Ltd. 2019-10-14
NCT04008004 A Study of EDP-514 in Healthy Subjects (Part 1) and Patients With Chronic Hepatitis B Virus Infection (Part 2) https://ClinicalTrials.gov/show/NCT04008004 Active, not recruiting Enanta Pharmaceuticals 2020-12-31
NCT03109730 Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03109730 Completed Assembly Biosciences 2018-03-31
NCT02862106 Second Stage:Open-label Study of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02862106 Completed Chongqing Jiachen Biotechnology Ltd. 2013-03-31
NCT01928511 Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy https://ClinicalTrials.gov/show/NCT01928511 Completed National University Health System, Singapore 2018-12-31
NCT01379508 Telbivudine or Tenofovir Treatment in HBeAg-negative Chronic Hepatitis B Patients Based on the Roadmap Concept https://ClinicalTrials.gov/show/NCT01379508 Completed Novartis 2015-12-10
NCT00838071 Evaluation of Serum Levels and Pharmacokinetics of a New Hepatitis B Immune Globulin Following Liver Transplantation https://ClinicalTrials.gov/show/NCT00838071 Completed Grifols Biologicals, LLC 2004-07-31
NCT00804622 Effects of Telbivudine and Tenofovir Disproxil Fumarate on the Kinetics of Hepatitis B Virus DNA in Chronic Hepatitis B (CHB) https://ClinicalTrials.gov/show/NCT00804622 Completed The University of Hong Kong 2009-06-30
NCT03625102 A Randomized, Double-Blind Trial of Antroquinonol in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03625102 Recruiting Golden Biotechnology Corporation 2020-12-31
NCT02862548 Efficacy and Safety of Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF)-Containing Regimens in Participants With Chronic Hepatitis B Virus (HBV) Infection and Stage 2 or Greater Chronic Kidney Disease Who Have Received a Liver Transplant https://ClinicalTrials.gov/show/NCT02862548 Active, not recruiting Gilead Sciences 2018-02-08
NCT02726789 Combination Treatment With REP 2139-Ca and Pegasys in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02726789 Completed Replicor Inc. 2016-09-30
NCT02845401 The “HBV e-Antigen Negative Disease-Directly Offers” Study: Treatment Withdrawal in Patients With Early-Antigen Negative Chronic HBV https://ClinicalTrials.gov/show/NCT02845401 Active, not recruiting California Pacific Medical Center Research Institute 2021-11-17
NCT02579382 Study to Evaluate the Safety, Tolerability, and Efficacy of Vesatolimod in Combination With Tenofovir Disoproxil Fumarate (TDF) in Adults With Chronic Hepatitis B (CHB) Infection Who Are Currently Not Being Treated https://ClinicalTrials.gov/show/NCT02579382 Completed Gilead Sciences 2017-01-16
NCT02565719 REP 2139-Mg and REP 2165-Mg Combination Therapy in Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT02565719 Completed Replicor Inc. 2019-05-31
NCT03468907 The Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuation https://ClinicalTrials.gov/show/NCT03468907 Completed Third Affiliated Hospital, Sun Yat-Sen University 2017-12-31
NCT00781105 Efficacy and Safety of Telbivudine 600mg Tablets in Chinese Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00781105 Completed Novartis 2010-09-16
NCT00736190 A Study to Evaluate Tenofovir Disoproxil Fumarate (DF) in Asian-American Adults With Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT00736190 Completed Gilead Sciences 2010-07-31
NCT00734162 Evaluation of Tenofovir Disoproxil Fumarate in Adolescents With Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT00734162 Completed Gilead Sciences 2011-03-31
NCT00718887 Suboptimal Responders to Adefovir Switching to Entecavir https://ClinicalTrials.gov/show/NCT00718887 Completed Bristol-Myers Squibb 2009-12-31
NCT00686790 Efficacy of Peginterferon Alfa-2b in Previously Untreated Subjects With Chronic Hepatitis B and D Co-infection (Study P04603) https://ClinicalTrials.gov/show/NCT00686790 Completed Merck Sharp & Dohme Corp. 2009-05-31
NCT00661076 ADVANCE Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) + Adefovir Dipivoxil in Patients With Hbe(-) Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00661076 Completed Hoffmann-La Roche 2011-05-31
NCT00651209 A Single-arm Study Evaluating the Efficacy and Safety of Telbivudine With or Without add-on Tenofovir in Adults With HBeAg-positive Chronic Hepatitis B (CHB) https://ClinicalTrials.gov/show/NCT00651209 Completed Novartis 2011-12-31
NCT00646503 Prospective Exploratory Study to Evaluate the Safety and Efficacy of Telbivudine in the Fifth Year of Treatment in Chinese Patients With Compensated Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00646503 Completed Novartis 2009-09-30
NCT00641082 A Double-Blind Randomized Clinical Trial Comparing the Safety and Antiviral Activity of 48-week Clevudine and Adefovir Dipivoxil in HBeAg(-) Chronic Hepatitis B With Compensated Liver Function https://ClinicalTrials.gov/show/NCT00641082 Completed Bukwang Pharmaceutical 2012-03-31
NCT00640588 Prospective Exploratory Study to Describe Hepatitis B Virus (HBV) Kinetics During Treatment With Telbivudine https://ClinicalTrials.gov/show/NCT00640588 Completed Novartis 2009-12-31
NCT00637663 Continuing Lamivudine Versus Switching to Entecavir in Patients Who Achieved Undetectable Hepatitis B Virus DNA https://ClinicalTrials.gov/show/NCT00637663 Completed Pusan National University Hospital 2010-11-30
NCT00625339 Continuing Lamivudine Versus Switching to Entecavir in Patients Who Achieved Undetectable HBV DNA https://ClinicalTrials.gov/show/NCT00625339 Completed Yonsei University 2010-11-30
NCT00614471 A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Entecavir in Treatment-Naive Patients With HBeAg-Positive Chronic Hepatitis B. https://ClinicalTrials.gov/show/NCT00614471 Completed Hoffmann-La Roche 2009-10-31
NCT00558818 Long-term Study With Clevudine https://ClinicalTrials.gov/show/NCT00558818 Completed Bukwang Pharmaceutical 2011-09-30
NCT00558493 Switching Study From Lamivudine to Clevudine in the Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT00558493 Completed Bukwang Pharmaceutical NA
NCT00537537 To Evaluate Antiviral Efficacy of Telbivudine in Hepatitis B Antigen Positive (HbeAg-positive) Compensated Chronic Hepatitis B (CHB) https://ClinicalTrials.gov/show/NCT00537537 Completed Novartis 2011-06-30
NCT00536627 Efficacy and Tolerance of Naked DNA Vaccine in Patients With Chronic B Hepatitis https://ClinicalTrials.gov/show/NCT00536627 Completed French National Agency for Research on AIDS and Viral Hepatitis 2010-11-30
NCT00536263 PegIntron Treatment of Chronic Hepatitis B e Antigen-Positive Patients (P05170/MK-4031-327) https://ClinicalTrials.gov/show/NCT00536263 Completed Merck Sharp & Dohme Corp. 2009-11-30
NCT00531167 Adding Adefovir Dipivoxil Versus Switching to Entecavir in Patients With Lamivudine-resistant Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00531167 Completed Korea University 2011-04-30
NCT00513968 Phase I Study to Investigate the Safety and Efficacy of HBV DNA Vaccine https://ClinicalTrials.gov/show/NCT00513968 Completed Genexine, Inc. 2010-04-30
NCT00507689 Truvada Versus Truvada Plus Hepatitis B Immunoglobulin (HBIg) in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplant https://ClinicalTrials.gov/show/NCT00507689 Completed Gilead Sciences 2011-05-31
NCT00507507 A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT) https://ClinicalTrials.gov/show/NCT00507507 Completed Gilead Sciences 2012-02-29
NCT00487747 A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Chronic Hepatitis B. https://ClinicalTrials.gov/show/NCT00487747 Completed Hoffmann-La Roche 2009-10-31
NCT00467545 An Extension to Viral Kinetics Study of Telbivudine and Entecavir in Adults With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00467545 Completed Novartis 2009-09-30
NCT00442572 SOFIA-LTT Study: A Study of Intermittent Long Term Treatment With PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Negative Chronic Hepatitis B (CHB). https://ClinicalTrials.gov/show/NCT00442572 Completed Hoffmann-La Roche 2012-04-23
NCT00441974 Adefovir Dipivoxil For The Treatment Of Chinese Compensated Chronic Hepatitis B(CHB)Patients https://ClinicalTrials.gov/show/NCT00441974 Completed GlaxoSmithKline 2008-09-30
NCT00436163 A Study of Peginterferon Alfa-2a (40KD) (PEGASYS®) in Participants With Hepatitis B Envelope Antigen (HBeAg) - Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00436163 Completed Hoffmann-La Roche 2010-05-31
NCT00435825 A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B (CHB). https://ClinicalTrials.gov/show/NCT00435825 Completed Hoffmann-La Roche 2010-12-31
NCT00423891 A Study of Entecavir in Pediatric Patients With Chronic Hepatitis B Virus (HBV)-Infection https://ClinicalTrials.gov/show/NCT00423891 Completed Bristol-Myers Squibb 2013-08-31
NCT00412529 Viral Kinetics Study of Telbivudine and Entecavir in Adults With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00412529 Completed Novartis 2008-02-29
NCT00410202 Entecavir Plus Adefovir Combination Therapy Versus Entecavir Monotherapy vs Therapy With Adefovir Plus Lamivudine for Chronic Hepatitis B Infected Subjects With Lamivudine-resistant Virus https://ClinicalTrials.gov/show/NCT00410202 Completed Bristol-Myers Squibb 2011-01-31
NCT00410072 Entecavir Plus Tenofovir Combination Therapy Versus Entecavir Monotherapy in Naive Subjects With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00410072 Completed Bristol-Myers Squibb 2010-10-31
NCT00403585 Study of Adefovir Dipivoxil for Korean Patients With Chronic Hepatitis B(CHB) Who Have Completed ADF 103814 https://ClinicalTrials.gov/show/NCT00403585 Completed GlaxoSmithKline 2008-04-30
NCT00397540 The Effect of Viral Load on Intrahepatic Recurrence in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC) https://ClinicalTrials.gov/show/NCT00397540 Completed Seoul National University Hospital 2011-05-31
NCT00395018 Antiviral Activity of Entecavir in Patients Receiving Liver Transplant Due to Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT00395018 Completed Bristol-Myers Squibb 2011-03-31
NCT00393484 A Study in Korea of Entecavir Versus Lamivudine in Adults With Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT00393484 Completed Bristol-Myers Squibb 2009-01-31
NCT00371761 PegIntron Versus Adefovir in the Treatment of Chronic Hepatitis B (CHB) e Antigen Positive Patients in Taiwan (P04498/MK-4031-278) https://ClinicalTrials.gov/show/NCT00371761 Completed Merck Sharp & Dohme Corp. 2009-02-28
NCT00371150 Effect of Entecavir in Blacks/African Americans and Hispanics With Chronic Hepatitis B Virus (HBV) Infection https://ClinicalTrials.gov/show/NCT00371150 Completed Bristol-Myers Squibb 2011-03-31
NCT00363155 KRN7000 in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00363155 Completed Foundation for Liver Research NA
NCT00354653 A Trial To Study The Effect Of Lamivudine In Adult Patients Who Suffer From Chronic Hepatitis B Alone https://ClinicalTrials.gov/show/NCT00354653 Completed ViiV Healthcare 2007-01-23
NCT00347009 Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis https://ClinicalTrials.gov/show/NCT00347009 Completed GlaxoSmithKline 2009-09-30
NCT00338780 Trial of Lamivudine Treatment in HBeAg Negative Chronic Hepatitis B Patients (in Asia) https://ClinicalTrials.gov/show/NCT00338780 Completed Chinese University of Hong Kong NA
NCT00324961 Adefovir Dipivoxil Tablets (10mg) In Chinese Subjects With HBe Antigen Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00324961 Completed GlaxoSmithKline 2009-01-31
NCT00316719 Adefovir Dipivoxil In Compensated Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT00316719 Completed GlaxoSmithKline 2008-01-31
NCT00307489 Treatment of Persistent Viremia (Virus in Blood) in Chronic Hepatitis B Subjects Already Receiving Adefovir Dipivoxil https://ClinicalTrials.gov/show/NCT00307489 Completed Gilead Sciences 2008-01-31
NCT00307242 Study Comparing the Safety of Switching From Lamivudine to Adefovir Dipivoxil Versus Overlapping Lamivudine and Adefovir Before Adefovir Dipivoxil Monotherapy in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00307242 Completed Thomas Jefferson University NA
NCT00298363 Study Comparing Tenofovir Disoproxil Fumarate (TDF), Emtricitabine (FTC)/TDF, and Entecavir (ETV) in the Treatment of Chronic HBV in Subjects With Decompensated Liver Disease. https://ClinicalTrials.gov/show/NCT00298363 Completed Gilead Sciences 2011-04-30
NCT00291616 Efficacy Study of Thymosin alpha1 & Pegylated Interferon-alpha2a to Treat Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00291616 Completed Seoul National University Hospital 2008-08-31
NCT00277576 Safety Study of HBV DNA Vaccine to Treat Patients With Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT00277576 Completed PowderMed NA
NCT00275938 Interferon Alpha 2b Plus Ribavirin for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00275938 Completed National Taiwan University Hospital NA
NCT00275652 A Comparison of the Drug Telbivudine (LdT) and Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis. https://ClinicalTrials.gov/show/NCT00275652 Completed Mayo Clinic 2007-08-31
NCT00230503 Dose-Ranging Study of Pradefovir in Patients With Compensated Hepatitis B https://ClinicalTrials.gov/show/NCT00230503 Completed Bausch Health Americas, Inc. 2006-12-31
NCT00230477 Hepsera Versus Hepsera Plus Lamivudine for Treatment of Chronic Hepatitis B in Patients With Normal ALT https://ClinicalTrials.gov/show/NCT00230477 Completed University of Washington NA
NCT00226447 Different Regimens of Pegylated Interferon and Lamivudine Combination Therapy in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT00226447 Completed Chinese University of Hong Kong 2006-07-31
NCT00226382 Treatment With Peginterferon Alfa-2a (40 KD) of Chronic Hepatitis B Patients, Who Have Failed Anti-viral Treatment https://ClinicalTrials.gov/show/NCT00226382 Completed Chinese University of Hong Kong 2008-04-30
NCT00142298 Telbivudine in Adults Previously Treated in Idenix-Sponsored Telbivudine Studies https://ClinicalTrials.gov/show/NCT00142298 Completed Novartis 2009-11-30
NCT00140725 Lamivudine Plus Interferon Versus Lamivudine For The Treatment Of HBeAg Positive Chronic Hepatitis B Virus (HBV) https://ClinicalTrials.gov/show/NCT00140725 Completed GlaxoSmithKline NA
NCT00132652 Switching Therapy From Lamivudine to Telbivudine Versus Continued Lamivudine in Adults With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00132652 Completed Novartis 2006-12-31
NCT00131742 Telbivudine Versus Lamivudine in Chinese Adults With Compensated Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00131742 Completed Novartis 2007-01-31
NCT00128544 Telbivudine Versus the Combination of Telbivudine and Valtorcitabine in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00128544 Completed Novartis 2007-05-31
NCT00124241 An Extension Study of Telbivudine, Lamivudine or Telbivudine Plus Lamivudine in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00124241 Completed Novartis 2003-02-28
NCT00120354 Long-Term Lamivudine Therapy for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00120354 Completed National Institutes of Health Clinical Center (CC) NA
NCT00117676 A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00117676 Completed Gilead Sciences 2007-04-30
NCT00116805 A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00116805 Completed Gilead Sciences 2007-05-31
NCT00115245 Telbivudine Versus Adefovir Dipivoxil in Adults With HBegAg-Positive, Compensated Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00115245 Completed Novartis 2006-08-31
NCT00111943 Safety and Acceptability of a Vaginal Microbicide https://ClinicalTrials.gov/show/NCT00111943 Completed National Institute of Allergy and Infectious Diseases (NIAID) NA
NCT00096785 Comparative Trial of Entecavir Versus Adefovir in the Treatment of Chronic Hepatitis B Infection https://ClinicalTrials.gov/show/NCT00096785 Completed Bristol-Myers Squibb 2006-01-31
NCT00095121 Safety and Efficacy of Adefovir Dipivoxil in Children and Adolescents With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00095121 Completed Gilead Sciences 2006-05-31
NCT00076336 Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis https://ClinicalTrials.gov/show/NCT00076336 Completed Novartis 2009-12-31
NCT00071201 Evaluate Efficacy, Safety and PK of Adefovir Dipivoxil Liquid Suspension in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00071201 Completed Gilead Sciences 2006-03-31
NCT00057265 A Randomized, Double Blind Trial of LdT (Telbivudine) Versus Lamivudine in Adults With Compensated Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00057265 Completed Novartis 2006-04-30
NCT00048945 Efficacy and Safety Study of Pegasys in the Treatment of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00048945 Completed Hoffmann-La Roche 2004-10-31
NCT00036608 A Phase III Study of Entecavir vs Lamivudine in Chronic Hepatitis B Subjects With Incomplete Response to Lamivudine https://ClinicalTrials.gov/show/NCT00036608 Completed Bristol-Myers Squibb 2005-02-28
NCT00035789 A Phase III Study of Entecavir vs Lamivudine in Adults With Chronic Hepatitis B Infection and Negative for Hepatitis B e Antigen https://ClinicalTrials.gov/show/NCT00035789 Completed Bristol-Myers Squibb 2005-05-31
NCT00035633 A Phase III Study of Entecavir vs Lamivudine in Adults With Chronic Hepatitis B Infection and Positive for Hepatitis B E Antigen https://ClinicalTrials.gov/show/NCT00035633 Completed Bristol-Myers Squibb 2005-02-28
NCT00034359 Safety and Antiviral Activity Study of ACH-126,443 (Beta-L-Fd4C) in Treatment Naive Adults With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT00034359 Completed Alexion Pharmaceuticals 2003-01-31
NCT00023309 Lamivudine and Adefovir to Treat Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00023309 Completed National Institutes of Health Clinical Center (CC) 2010-04-30
NCT00625560 Continuing Lamivudine vs Switching to Entecavir in Patients With Detectable HBV DNA https://ClinicalTrials.gov/show/NCT00625560 Completed Yonsei University 2009-11-30
NCT00023153 Lamivudine and Adefovir to Treat Chronic Hepatitis B Infection in People With and Without HIV Infection https://ClinicalTrials.gov/show/NCT00023153 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001457 Lamivudine for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00001457 Completed National Institutes of Health Clinical Center (CC) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03358108 A Prospective,Observational Follow-up Study of Nucleoside Treated Patients With Chronic Hepatitis B (OCEAN Study) https://ClinicalTrials.gov/show/NCT03358108 Recruiting Tongji Hospital 2020-12-01
NCT03329820 Quality of Life and Health Utility of Patients With CHB Infections https://ClinicalTrials.gov/show/NCT03329820 Completed The University of Hong Kong 2009-06-30
NCT03300414 Biologic Basis of Liver Cancer From Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03300414 Completed University of California, Davis 2018-12-14
NCT03215732 Cross Sectional Survey on the Burden and Impacts of Chronic Hepatitis B in the Rural Area of Niakhar, Senegal https://ClinicalTrials.gov/show/NCT03215732 Completed French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) 2019-07-31
NCT03158818 Chronic Hepatitis B Virus Infection in Zambia https://ClinicalTrials.gov/show/NCT03158818 Recruiting University of Alabama at Birmingham 2021-01-31
NCT03149627 Chronic Hepatitis B Virus Clinical Epidemiology in a Representative Sample of Zambian Adults https://ClinicalTrials.gov/show/NCT03149627 Completed University of Alabama at Birmingham 2018-12-19
NCT03097952 “Real-life” Cohort Study on Patients With Chronic HBV Infection in Jiangsu https://ClinicalTrials.gov/show/NCT03097952 Recruiting The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 2030-12-31
NCT03042481 Off-therapy Response After Stopping Entecavir or Tenofovir https://ClinicalTrials.gov/show/NCT03042481 Recruiting Kaohsiung Medical University Chung-Ho Memorial Hospital 2019-05-31
NCT02863757 Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease https://ClinicalTrials.gov/show/NCT02863757 Recruiting Humanity and Health Research Centre 2026-12-31
NCT02791386 Rescue Treatment Pattern, Drug Resistance Recurrence, and Direct Medical Costs Associated With Chinese Patients With Chronic Hepatitis B and Drug Resistance to Nucleot(s)Ide Analogue Therapy https://ClinicalTrials.gov/show/NCT02791386 Completed Bristol-Myers Squibb 2017-10-30
NCT02719808 Study of Antiretroviral Therapy to Prevent HBV Intrauterine Infection https://ClinicalTrials.gov/show/NCT02719808 Recruiting First Affiliated Hospital Xi’an Jiaotong University 2022-12-31
NCT02582333 Clinical Course Study in Chronic Hepatitis B After Nucleos(t)Ide Analogue Therapy https://ClinicalTrials.gov/show/NCT02582333 Recruiting Taichung Veterans General Hospital 2020-10-31
NCT02566148 Life Course, HIV and Hepatitis B Among African Migrants Living in Ile-de-France https://ClinicalTrials.gov/show/NCT02566148 Completed French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) 2012-02-29
NCT02533544 Treatment Efficacy and Safety of Tenofovir Disoproxil Fumarate (TDF) in naïve Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02533544 Completed The Catholic University of Korea 2018-10-31
NCT02511743 Knowledge and Practice of Chinese Medical Specialists Regarding Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT02511743 Completed Peking University First Hospital 2015-11-30
NCT02387463 Efficacy of Extended Peginterferon Alpha 2a Treatment in HBeAg Positive Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT02387463 Completed Beijing Ditan Hospital 2017-05-21
NCT02336399 Sustained HBsAg and Viral Response in Patients Achieved HBsAg Loss by Interferon Treatment https://ClinicalTrials.gov/show/NCT02336399 Active, not recruiting Beijing Ditan Hospital 2016-12-31
NCT02267473 Hepatitis B Patients Under Oral Nucleos(t)Ide Treatment With Intermittent Assessment of Kidney Function https://ClinicalTrials.gov/show/NCT02267473 Active, not recruiting Johann Wolfgang Goethe University Hospital 2020-10-31
NCT02201407 An Observational Study in Participants With Chronic Hepatitis B (CHB) Receiving Therapy With Peginterferon Alfa-2a 40 Kilodaltons (kD) (PEGASYS) - The PRO B Study https://ClinicalTrials.gov/show/NCT02201407 Completed Hoffmann-La Roche 2017-04-10
NCT02167113 Collection of Samples for the Clinical Evaluation of the Aptima HBV (Hepatitis B Virus) Quant (Quantification) Assay https://ClinicalTrials.gov/show/NCT02167113 Completed Hologic, Inc. 2016-02-29
NCT02129829 PROLIFICA - West African Treatment Cohort for Hepatitis B https://ClinicalTrials.gov/show/NCT02129829 Active, not recruiting Imperial College London 2020-04-01
NCT02125071 Study on the Pharmacokinetic Characteristics of I.V. Hepabig Injection Used for Prevention of Hepatitis B Relapse After Liver Transplantation https://ClinicalTrials.gov/show/NCT02125071 Completed Seoul St. Mary’s Hospital 2015-08-31
NCT02075294 Efficacy and Safety Study of Adefovir and Entecavir for Elderly With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02075294 Completed Beijing 302 Hospital 2012-10-31
NCT02069678 Serum Hepatitis B Surface Antigen Levels to Guide the Stopping of Entecavir in HBeAg-negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02069678 Completed Chinese University of Hong Kong 2013-09-30
NCT01311947 Hepatitis B Virus Mutants and the Therapeutic Effect of Peginterferon Alfa-2a in HBeAg-Positive Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01311947 Completed China Medical University Hospital 2012-03-31
NCT01298037 HBRN: Immune Regulation and Costimulation in Natural History of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01298037 Active, not recruiting University of Pennsylvania 2021-05-31
NCT01283074 An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HbeAg-negative Chronic Hepatitis B (Perseas) https://ClinicalTrials.gov/show/NCT01283074 Completed Hoffmann-La Roche 2012-11-30
NCT02019966 A Korean Cohort Study of TDF Rescue Therapy for Difficult-to-treat CHB Patients: a Comparison Between TDF Monotherapy and TDF-based Combination Therapy https://ClinicalTrials.gov/show/NCT02019966 Completed Yonsei University 2017-08-04
NCT02005146 Retrospective Observational Study to Define HBsAg Loss With or Without Seroconversion to antiHBs in Patients With Chronic Hepatitis by B Virus Treated With Nucleoside/Nucleotide Analogs https://ClinicalTrials.gov/show/NCT02005146 Completed Andalusian Network for Design and Translation of Advanced Therapies 2014-12-31
NCT01958229 Efficacy Study of Telbivudine in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT01958229 Completed National Taiwan University Hospital 2012-03-31
NCT01957618 The Follow-up Study of Chronic Hepatitis B Patients With Liver Cirrhosis Receiving Anti-HBV Therapy https://ClinicalTrials.gov/show/NCT01957618 Enrolling by invitation National Taiwan University Hospital 2012-01-31
NCT01855997 A Study to Collect Blood Biomarker Samples From Participants With Chronic Hepatitis B (CHB) Who Received Treatment With Pegasys (Peginterferon Alfa-2a) ± Nucleoside/Nucleotide Analogue https://ClinicalTrials.gov/show/NCT01855997 Completed Hoffmann-La Roche 2014-11-28
NCT01826760 Study of the Model to Predict 3-month Mortality Risk of Acute-on-chronic Hepatitis B Liver Failure https://ClinicalTrials.gov/show/NCT01826760 Completed Wenzhou Medical University 2010-05-31
NCT01796457 HBRN: Immune Regulation and Costimulation in Natural History and Therapeutic Outcome of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01796457 Active, not recruiting University of Pennsylvania 2020-07-31
NCT01772121 Observational Study on Prevalence of Host and Viral Genotypes in Chronic Hepatitis B and Hepatitis C Patients in India https://ClinicalTrials.gov/show/NCT01772121 Completed Gilead Sciences 2012-10-31
NCT01734018 An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Positive or HBeAg-Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01734018 Completed Hoffmann-La Roche 2012-08-31
NCT01732354 Study for Consolidation Period of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01732354 Completed Tainan Municipal Hospital 2013-11-20
NCT01732081 “Real-life” Cohort of Patients With Chronic Hepatitis B Virus Infection https://ClinicalTrials.gov/show/NCT01732081 Recruiting University Hospital, Strasbourg, France 2021-01-31
NCT01730508 An Observational Study of Pegasys (Peginterferon Alfa-2a) in Chinese Patients With HBeAg Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01730508 Completed Hoffmann-La Roche 2017-06-25
NCT03350074 HBV Envelope Proteins Variability on HBs Antigen Clearance Under Nucleos(t)Ide Analogue Therapy https://ClinicalTrials.gov/show/NCT03350074 Completed Central Hospital, Nancy, France 2016-05-01
NCT01705704 A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01705704 Completed Hoffmann-La Roche 2013-02-28
NCT01667432 An Observational Study of Peginterferon Alfa-2a (PEGASYS®) in Patients With HBeAg Positive or HBeAg Negative Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01667432 Completed Hoffmann-La Roche 2014-08-12
NCT01645969 A Follow-Up Study of Patients With HBeAg Positive Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML22265 https://ClinicalTrials.gov/show/NCT01645969 Completed Hoffmann-La Roche 2012-10-31
NCT01548820 Resistance to Lamivudine in HBV Egyptian Patients https://ClinicalTrials.gov/show/NCT01548820 Completed Ain Shams University 2012-11-30
NCT01531166 A Cohort Study in Korean Patients With Chronic Hepatitis B (CHB) Receiving Pegylated Interferon https://ClinicalTrials.gov/show/NCT01531166 Completed Yonsei University 2014-08-31
NCT01401400 Genetic Study of Peginterferon Treatment in Hepatitis B Patients: The GIANT-B Study https://ClinicalTrials.gov/show/NCT01401400 Completed Foundation for Liver Research 2015-06-30
NCT01376154 Special Drug Use Investigation for ZEFIX (Lamivudine) Tablet (HBV Cirrhosis) https://ClinicalTrials.gov/show/NCT01376154 Completed GlaxoSmithKline 2009-12-31
NCT01356901 Persistence, Adherence and Clinical Effectiveness of Entecavir in Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT01356901 Completed Bristol-Myers Squibb 2015-01-31
NCT01323452 Entecavir for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01323452 Completed Foundation for Liver Research 2011-01-31
NCT04237376 Chronic HBV Infection in Pregnant Women Taking TAF to Prevent Vertical Transmission https://ClinicalTrials.gov/show/NCT04237376 Recruiting New Discovery LLC 2020-09-30
NCT04211805 Maternal Therapy With TAF Versus TDF to Prevent Vertical Transmission of Hepatitis B https://ClinicalTrials.gov/show/NCT04211805 Recruiting New Discovery LLC 2021-09-30
NCT04160897 Risk of Hepatocellular Carcinoma in Patients Treated With ETV vs TDF for Chronic Hepatitis B With Compensated Cirrhosis https://ClinicalTrials.gov/show/NCT04160897 Enrolling by invitation Ruijin Hospital 2020-10-31
NCT04135235 Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis B https://ClinicalTrials.gov/show/NCT04135235 Recruiting Beijing Ditan Hospital 2021-08-01
NCT04032275 Correlation Between Virus and Biochemical Characteristics and Liver Histological Damage in Untreated Chronic HBV Infection https://ClinicalTrials.gov/show/NCT04032275 Completed Beijing Ditan Hospital 2018-12-30
NCT04030039 Cohort Study of Clinical Outcomes in Chronic HBV Infection Patients With Low HBsAg Under Unplanned Intervention https://ClinicalTrials.gov/show/NCT04030039 Recruiting Beijing Ditan Hospital 2020-12-30
NCT04028856 Cohort Study of Efficacy and Safety of Interferon Intermittent Treatment of Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT04028856 Completed Beijing Ditan Hospital 2019-06-30
NCT03977857 Computed Tomography Liver Volume for Predicting Short-term Mortality in Hepatitis B‐Acute‐on‐Chronic Liver Failure https://ClinicalTrials.gov/show/NCT03977857 Completed First Affiliated Hospital Xi’an Jiaotong University 2019-12-31
NCT03909191 Serum HBV RNA Value on Chronic Hepatitis B Virus Infection Manage https://ClinicalTrials.gov/show/NCT03909191 Active, not recruiting Changhai Hospital 2020-05-01
NCT03777969 Prediction System of Clinical Endpoint Events for Chronic Hepatitis B Patients https://ClinicalTrials.gov/show/NCT03777969 Recruiting Beijing Friendship Hospital 2020-12-31
NCT03752658 TAF Real World Study for Universal Effectiveness https://ClinicalTrials.gov/show/NCT03752658 Recruiting Tongji Hospital 2023-05-01
NCT03740789 Evaluation of Antiviral Indications on Chronic HBV Infection With Different Transaminase Levels https://ClinicalTrials.gov/show/NCT03740789 Active, not recruiting First Affiliated Hospital Xi’an Jiaotong University 2019-04-30
NCT03692897 An Observational Study of Patients Undergoing Therapy for Chronic Hepatitis B (HBV) Infection https://ClinicalTrials.gov/show/NCT03692897 Active, not recruiting Target PharmaSolutions, Inc. 2023-01-31
NCT03643172 Terminator 2 Register https://ClinicalTrials.gov/show/NCT03643172 Recruiting Hannover Medical School 2020-07-31
NCT03642340 A Post-marketing Surveillance to Assess Safety and Efficacy of Besivo https://ClinicalTrials.gov/show/NCT03642340 Recruiting IlDong Pharmaceutical Co Ltd 2023-05-14
NCT03559790 Treatment Efficacy and Safety of TDF-TAF Switch Study in South Korea https://ClinicalTrials.gov/show/NCT03559790 Recruiting The Catholic University of Korea 2020-08-31
NCT03459768 Cohort Study on People Who Inject Drugs in Senegal https://ClinicalTrials.gov/show/NCT03459768 Active, not recruiting French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) 2020-02-29
NCT03426618 A Real-World Observational Study for the Safety and Efficacy of Baraclude in Korean Pediatric Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT03426618 Completed Bristol-Myers Squibb 2019-03-13
NCT01267162 Long-term Study on Anti-HBV Effect of Tenofovir and Resistance Surveillance in Asian-American Adult Patients https://ClinicalTrials.gov/show/NCT01267162 Completed Medical Procare PLLC 2013-11-30
NCT01264107 An Open Study to Evaluate the Sustained Effect in Patients Showing Virological Responses With Muscle-related Symptom of Chronic Hepatitis B Patients Who Received Clevudine https://ClinicalTrials.gov/show/NCT01264107 Completed Bukwang Pharmaceutical 2012-01-31
NCT01163240 Epidemiological Study in Children and Adolescents With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01163240 Completed Novartis 2011-09-30
NCT01155427 Systematic Review of Antiretroviral Treatments for Chronic Hepatitis B (CHB) https://ClinicalTrials.gov/show/NCT01155427 Completed Bristol-Myers Squibb 2010-04-30
NCT01128686 Lamivudine(LAM) Good Responder Study https://ClinicalTrials.gov/show/NCT01128686 Completed ViiV Healthcare 2011-06-30
NCT01107483 Observe Change of Endotoxaemia and Related Mediators in Patients With Chronic Hepatitis B Virus (HBV) Infection https://ClinicalTrials.gov/show/NCT01107483 Completed Sun Yat-sen University 2010-02-28
NCT01090531 Patients With Chronic Hepatitis B and Low Viremia Not Receiving Antiviral Therapy https://ClinicalTrials.gov/show/NCT01090531 Active, not recruiting Johann Wolfgang Goethe University Hospital 2021-08-31
NCT01011738 An Observational Cohort Study in Patients With Chronic Hepatitis B Receiving Pegasys https://ClinicalTrials.gov/show/NCT01011738 Completed Hoffmann-La Roche 2014-11-18
NCT00970216 Study of Telbivudine in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00970216 Completed Chang Gung Memorial Hospital 2016-01-31
NCT00956891 Therapeutic Effects of Liver Failure Patients Caused by Chronic Hepatitis B After Autologous MSCs Transplantation https://ClinicalTrials.gov/show/NCT00956891 Completed Sun Yat-sen University 2009-06-30
NCT03181607 Efficacy and Adverse Effects of Nucleoside Analogues (TDF/LDT) in Preventing Mother-to-child Transmission of HBV https://ClinicalTrials.gov/show/NCT03181607 Enrolling by invitation The Third Affiliated Hospital of Guangzhou Medical University 2019-05-26
NCT01581554 Withdrawal of Therapy After Long-Term Antiviral Treatment for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01581554 Completed National Institutes of Health Clinical Center (CC) NA
NCT03587467 Study on Gut Microbiota in Chronic HBV Infected Patients https://ClinicalTrials.gov/show/NCT03587467 Recruiting Zhongshan Hospital Xiamen University 2020-12-01
NCT02995252 The HOPE Study: Characterizing Patients With Hepatitis B and C https://ClinicalTrials.gov/show/NCT02995252 Recruiting University of Maryland, Baltimore 2020-01-31
NCT02974829 REALM China Extension Study https://ClinicalTrials.gov/show/NCT02974829 Recruiting Nanfang Hospital of Southern Medical University 2022-01-31
NCT02876419 A Long Term Follow-up Study of Patients From the REP 301 Protocol https://ClinicalTrials.gov/show/NCT02876419 Active, not recruiting Replicor Inc. 2019-11-13
NCT03181113 Long-term Benefit in Chronic Hepatitis B Patients After Standard Peginterferon Alfa Therapy https://ClinicalTrials.gov/show/NCT03181113 Enrolling by invitation Xiamen Amoytop Biotech Co., Ltd. 2020-12-31
NCT00645736 CHARM: Chronic Hepatitis B Antihepadnaviral Resistance Mutation Study https://ClinicalTrials.gov/show/NCT00645736 Completed Gilead Sciences 2008-10-31
NCT00512941 Laboratory Profile of Hepatitis B and C in Users of a Reference Service https://ClinicalTrials.gov/show/NCT00512941 Completed UPECLIN HC FM Botucatu Unesp NA
NCT00388674 Study of Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection https://ClinicalTrials.gov/show/NCT00388674 Completed Bristol-Myers Squibb 2016-10-26
NCT00263614 Evaluation of Chronic HBV Patients w/Evidence of HBV Replication and Normal or Minimally Elevated Liver Transaminases. https://ClinicalTrials.gov/show/NCT00263614 Completed Gilead Sciences NA
NCT00199732 Evaluation of cccDNA and Total HBV DNA Kinetics in Lymphocytes, Total Blood and Serum in Chronic Hepatitis B Patients Treated With Adefovir Dipivoxil and Peg Interferon Alpha 2a https://ClinicalTrials.gov/show/NCT00199732 Completed University Hospital, Limoges 2009-07-31
NCT00155155 Studies of Immune Responses in Patients With Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT00155155 Completed National Taiwan University Hospital 2008-04-30
NCT00146705 Long Term Follow-up of Pegylated-Interferon Alpha-2b https://ClinicalTrials.gov/show/NCT00146705 Completed Foundation for Liver Research NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03108794 A Nation-wide Hospital-based Hepatitis B Registry:China Registry of Hepatitis B https://ClinicalTrials.gov/show/NCT03108794 Recruiting Beijing Friendship Hospital 2022-12-31
NCT02766933 Cameroon Baptist Convention Health Board Chronic Hepatitis B Cohort Study https://ClinicalTrials.gov/show/NCT02766933 Active, not recruiting Mayo Clinic 2022-05-31
NCT02263755 Establishment of Retrospective and Prospective Multicenter Cohort for Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT02263755 Completed Yonsei University 2015-06-25
NCT01908660 Hepatic Safety of Currently Used Antiretroviral Regimens in Patients With Chronic Hepatitis Under Real Life Conditions https://ClinicalTrials.gov/show/NCT01908660 Completed Valme University Hospital 2015-09-30
NCT04139850 The Establishment of Korean Hepatitis B Patients Cohort https://ClinicalTrials.gov/show/NCT04139850 Recruiting Yonsei University 2026-08-31
NCT03597633 Tenofovir Combination or Mono-therapy for MDR CHB https://ClinicalTrials.gov/show/NCT03597633 Active, not recruiting Korea University 2018-12-31
NCT03425994 Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide as Maintenance Treatment for HIV/HBV-coinfection https://ClinicalTrials.gov/show/NCT03425994 Active, not recruiting National Taiwan University Hospital 2019-02-22
NCT03734783 IL-35+Breg/Il-35 Effect on T Cell Immune in Patients With CHB https://ClinicalTrials.gov/show/NCT03734783 Completed Changhai Hospital 2019-11-15
NCT02031913 Prospective Cohort Study of Association of Insulin Resistance/Steatosis With Hepatic Fibrosis in CHB and NAFLD https://ClinicalTrials.gov/show/NCT02031913 Recruiting Seoul National University Boramae Hospital 2022-11-30
NCT01679769 Prospective Study In Noninvasive Evaluation of Hepatic Fibrosis in Chronic Hepatitis B https://ClinicalTrials.gov/show/NCT01679769 Completed Peking University First Hospital 2015-10-31